The 221 Remington Fireball was introduced in 1963 in Remington's XP-100 bolt-action pistol. Based on the 222 Remington case shortened to 1.4 inches, it was designed for maximum efficiency in a 12-inch pistol barrel as part of a growing interest in long-range handgunning. Velocity is a very credible 2995 feet per second with a 50-grain bullet, making it an excellent medium-range varmint cartridge in both handguns and rifles. Remington is the only manufacturer offering 221 Fireball ammo, but a variety of specialty handguns and some bolt-action rifles have been chambered to it.